Tryst Nightclub Event Calendar - May 2025

Few nightclub names capture the essence of the space better than Tryst Nightclub inside the Las Vegas Wynn. For one night you will fall in love, hold a romance that is unmistakable, and then just like that, it will disappear with only a memory to hold on to. The lifeblood of any club is its music, design, the kind of crowd it draws, and the level of VIP and table service it offers. Tryst brings the best of all of these and more, making it one of the best nightclubs in Vegas, no matter how hard younger competitors try to outdo its edgy novelties.

Tryst isn't your newest, hottest Las Vegas club or even the biggest at 12,000 square feet. But its features, including VIP booths nestled near an actual 90-foot waterfall and seductive décor and embellishments in shades of red, all add up to a haven for fun and a sanctuary for rendezvous or two.

Tryst brings you and your crew an ever-expanding list of big name resident DJs that will certainly stick with you long after the sun comes up, including Party Rock Anthem and most notably, Lil Jon. Hip hop and Top 40 make the perfect soundtrack in this velvety smooth atmosphere of vintage lipstick red, gold hardware, and amber lighting. Tryst was largely the inspiration behind XS at the neighboring Encore, but on a smaller scale, so when deadmau5 — one of the club's resident DJs — puts on one of his concert-style performances in the intimate venue, you'll feel like you can almost reach out and touch his mouse ears.

But there is much more to Tryst than great music and a flashy interior. An outdoor piazza complete with poolside drinks and dancing and a seriously sexy ambiance make the night one you wish would never end. Tryst opens at 10 p.m. and rocks ’til dawn at 4 a.m., all the while the table and bottle service flows.

Wondering what to wear to Tryst? Don’t wander in dressed in tees or tanks and sneakers, but there’s no need to do it up like Bond either. Wear a collared shirt with classically styled dungarees will do for dudes, who are also warned to leave their track suits, sports team jerseys, hats, and sneakers at home. The ladies? It's your call — the night belongs to you at Tryst.